Adipocyte Microenvironment: Everybody in the Neighborhood Talks about the Temperature

Farnaz Shamsi; Yu-Hua Tseng; C Ronald Kahn

doi:10.1016/j.cmet.2020.12.012

Adipocyte Microenvironment: Everybody in the Neighborhood Talks about the Temperature

Cell Metab. 2021 Jan 5;33(1):4-6. doi: 10.1016/j.cmet.2020.12.012.

Authors

Farnaz Shamsi¹, Yu-Hua Tseng¹, C Ronald Kahn²

Affiliations

¹ Joslin Diabetes Center, Section on Integrative Physiology and Metabolism, Harvard Medical School, Boston, MA, USA.
² Joslin Diabetes Center, Section on Integrative Physiology and Metabolism, Harvard Medical School, Boston, MA, USA. Electronic address: c.ronald.kahn@joslin.harvard.edu.

Abstract

Adipose tissue is composed of a variety of cells distributed in different depots and playing various metabolic roles. In a recent issue of Nature, Sun et al. (2020) use snRNA-seq and functional studies to identify a population of adipocytes that can suppress the thermogenic activity of neighboring adipocytes by secretion of acetate.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Adipocytes
Adipose Tissue
RNA, Small Nuclear*
Temperature
Thermogenesis*

Substances

RNA, Small Nuclear

Abstract

Publication types

MeSH terms

Substances

Grants and funding