Primordial Protein Tails

Mol Cell. 2021 Jan 7;81(1):6-7. doi: 10.1016/j.molcel.2020.12.032.


C-terminal tailing is an ancient and conserved form of peptide synthesis that protects cells from incomplete and potentially toxic translation products. Filbeck et al. (2020) and Crowe-McAuliffe et al. (2020) use structural, genetic, and biochemical approaches to elucidate the mechanisms driving C-terminal tailing.

Publication types

  • Comment

MeSH terms

  • Bacteria*
  • Quality Control
  • Ribosomes*