Effect of a postpartum prescription for pertussis vaccine: a before-and-after study

J Gynecol Obstet Hum Reprod. 2021 Apr;50(4):102050. doi: 10.1016/j.jogoh.2020.102050. Epub 2021 Jan 6.

Abstract

Background: Among the strategies to encourage pregnant women to be vaccinated against pertussis in the postpartum period, that of giving them a prescription has been evaluated only sparsely.

Objective: To measure the effect of giving women who are not immunized against pertussis a prescription for the vaccine at discharge from the maternity unit.

Material and methods: Single-center before-and-after study (2011: before; 2015: after). All women received both oral and written information about vaccination against pertussis. During the after period, they were also specifically asked their immunization status during pregnancy. Those currently unimmunized received a written prescription for it at discharge.

Results: Among the women unimmunized at delivery, the percentage who were vaccinated postpartum climbed from 17 to 42% between 2011 and 2015 (p < 0.001), while the percentage of their unimmunized partners who were vaccinated remained stable (27 and 29%, p = 0.74). During this time, the percentage of women immunized against pertussis at the beginning of pregnancy rose from 32 to 52% (p < 0.001). Finally, the percentage of all women protected against this disease postpartum climbed from 44 to 72% between these two periods (p < 0.001).

Conclusions: In the postpartum period, giving a prescription for pertussis vaccine to women unimmunized is accompanied by a significant elevation in their vaccination rate. Nevertheless, this rate remains low and better strategies have to be implemented.

Keywords: Cocooning strategy; Pertussis; Postpartum; Pregnancy; Prescription; Vaccination.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Controlled Before-After Studies*
  • Family Health
  • Female
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Parity
  • Patient Discharge
  • Pertussis Vaccine / administration & dosage*
  • Postpartum Period*
  • Pregnancy
  • Prescriptions*
  • Spouses / statistics & numerical data
  • Surveys and Questionnaires
  • Vaccination / statistics & numerical data*
  • Whooping Cough / prevention & control*

Substances

  • Pertussis Vaccine