Alterations of Functional Connectivity During the Resting State and Their Associations With Visual Memory in College Students Who Binge Drink

Bo-Mi Kim; Myung-Sun Kim; June Sic Kim

doi:10.3389/fnhum.2020.600437

Alterations of Functional Connectivity During the Resting State and Their Associations With Visual Memory in College Students Who Binge Drink

Front Hum Neurosci. 2020 Dec 1:14:600437. doi: 10.3389/fnhum.2020.600437. eCollection 2020.

Authors

Bo-Mi Kim¹, Myung-Sun Kim¹, June Sic Kim²

Affiliations

¹ Department of Psychology, Sungshin Women's University, Seoul, South Korea.
² Research Institute of Basic Sciences, Seoul National University, Seoul, South Korea.

Abstract

This study investigated the characteristics of neural oscillation and functional connectivity (FC) in college students engaging in binge drinking (BD) using resting-state electroencephalography (EEG). Also, the associations of visual memory, evaluated by the Rey-Osterrieth Complex Figure Test (RCFT), and neural oscillation with FC during the resting state were investigated. The BD (n = 35) and non-BD (n = 35) groups were selected based on scores of the Korean version of the Alcohol use disorders (AUDs) Identification Test and the Alcohol Use Questionnaire. EEG was performed for 6 min while the participants rested with eyes closed. The theta, lower-alpha, and upper alpha powers did not differ between the BD and non-BD groups. Concerning FC, the BD group exhibited stronger theta coherence than that of the non-BD group, and in the lower and upper alpha bands, the BD group showed stronger coherence in some areas but weaker coherence in others compared with the non-BD group. However, these significant results were not observed after Bonferroni correction. The BD group showed significantly lower delayed recall scores on the RCFT than did the non-BD group. A positive correlation between the left prefrontal-parietal-occipital midline connection and performance on the delayed recall of the RCFT was observed in the BD group. The present results could suggest that binge drinkers have alterations in brain FC, which may be related to their visual memory deficits.

Keywords: Rey-Osterrieth complex figure test; binge drinking; functional connectivity; lower alpha; neural oscillation; theta; upper alpha; visual memory.