A single nucleotide distinguishes the SARS-CoV-2 in the Wuhan outbreak in December 2019 from that in Beijing-Xinfadi in June 2020, China

Y-Q Pan; A N Bahoussi; F Guo; L Xing

doi:10.1016/j.nmni.2020.100835

A single nucleotide distinguishes the SARS-CoV-2 in the Wuhan outbreak in December 2019 from that in Beijing-Xinfadi in June 2020, China

New Microbes New Infect. 2020 Dec 15:39:100835. doi: 10.1016/j.nmni.2020.100835. eCollection 2021 Jan.

Authors

Y-Q Pan¹, A N Bahoussi¹, F Guo¹, L Xing^{1

2

3}

Affiliations

¹ Institute of Biomedical Sciences, Shanxi University, Taiyuan, China.
² Key Laboratory of Medical Molecular Cell Biology of Shanxi Province, Shanxi University, Taiyuan, China.
³ Shanxi Provincial Key Laboratory for Prevention and Treatment of Major Infectious Diseases, Taiyuan, China.

Abstract

Two major locally transmitted outbreaks of coronavirus disease 2019 occurred in China, one in Wuhan from December 2019 to April 2020, another in Beijing-Xinfadi in June 2020. Severe acute respiratory syndrome coronavirus 2 isolated from these two outbreaks can be distinguished by a conserved pyrimidine nucleotide located at nucleotide position 241 in the 5'-untranslated region of the virus genome.

Keywords: 5′-untranslated region; Beijing; Wuhan; coronavirus disease 2019; pyrimidine.

Publication types

Case Reports