A blind trial of silicone chamber fluid in nerve regeneration in the rat

Exp Neurol. 1988 Mar;99(3):765-7. doi: 10.1016/0014-4886(88)90190-2.


The nerve growth-promoting effects of the fluid accumulating in vivo from 1 to 28 days within silicone chambers were tested on the sciatic nerves of rats. We measured the elongation of sensory axons following nerve transection repaired by means of fibrin sealant allowing local application of the fluid. We found no difference between transections treated with chamber fluid and controls.

MeSH terms

  • Animals
  • Axons / physiology
  • Equipment and Supplies
  • Nerve Regeneration*
  • Rats
  • Silicones


  • Silicones