[A case of advanced pancreatic cancer with oculomotor nerve palsy caused by herpes zoster after introduction of gemcitabine plus nab-paclitaxel]

Nihon Shokakibyo Gakkai Zasshi. 2021;118(1):86-92. doi: 10.11405/nisshoshi.118.86.
[Article in Japanese]

Abstract

A 76-year-old woman was admitted to our hospital due to diabetes and was diagnosed with advanced pancreatic cancer for which she received gemcitabine plus nab-paclitaxel. Fourteen days later, eruptions were observed in the first division of the right trigeminal nerve;she was then diagnosed with herpes zoster and was successfully treated with antiviral therapy. Seven days after the herpes zoster infection, right ophthalmoplegia appeared. Oculomotor nerve palsy secondary to herpes zoster ophthalmicus was suspected and she was treated with steroid pulse therapy. Her symptoms improved, and chemotherapy was able to be continued. Her ophthalmoplegia had almost fully resolved 41 days after the onset of herpes zoster infection.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir
  • Aged
  • Albumins
  • Antiviral Agents*
  • Deoxycytidine / analogs & derivatives
  • Female
  • Gemcitabine
  • Humans
  • Oculomotor Nerve Diseases* / drug therapy
  • Oculomotor Nerve Diseases* / etiology
  • Paclitaxel
  • Pancreatic Neoplasms*

Substances

  • 130-nm albumin-bound paclitaxel
  • Albumins
  • Antiviral Agents
  • Deoxycytidine
  • Paclitaxel
  • Acyclovir
  • Gemcitabine