Cognitive Stimulation Therapy for Older Adults With Mild-to-Moderate Dementia in Italy: Effects on Cognitive Functioning, and on Emotional and Neuropsychiatric Symptoms

J Gerontol B Psychol Sci Soc Sci. 2021 Oct 30;76(9):1700-1710. doi: 10.1093/geronb/gbab007.

Abstract

Objectives: Cognitive Stimulation Therapy (CST) is one of the most popular evidence-based interventions for people with dementia. The aim of the present study was to assess the effectiveness in the short- and long-term (on completing the treatment and 3 months later) of an Italian adaptation of the CST protocol (CST-IT).

Method: Older adults with mild-to-moderate dementia at 16 residential care homes were randomly assigned to a CST-IT group (N = 123) or an active control group (N = 102). The following domains were examined for potential benefits: general cognitive functioning (Mini-Mental State Examination [MMSE] and the Alzheimer's Disease Assessment Scale-Cognitive subscale [ADAS-Cog]), language (Narrative Language Test), mood and behavior (Cornell scale and Neuropsychiatric Inventory), everyday life functioning (Disability Assessment for Dementia), and quality of life (Quality of Life-Alzheimer's Disease scale).

Results: At both the short- and long-term assessments, the CST-IT group's MMSE scores remained stable, while the control group's scores decreased slightly from pretest to posttest and at follow-up. The CST-IT group also had short-term benefits in other cognitive measures (ADAS-Cog and Narrative Language Test) and mood and behavior measures, which were generally maintained at follow-up. No other differences were observed.

Discussion: The effectiveness of CST in sustaining cognitive and emotional functioning, and counteracting the progression of behavioral/neuropsychiatric symptoms in people with dementia was confirmed, and a long-term benefit was demonstrated. CST is a promising option for the treatment of people with dementia in clinical practice.

Keywords: Behavioral symptoms; Cognition; Cognitive stimulation; Dementia; Depression.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Activities of Daily Living
  • Aged
  • Aged, 80 and over
  • Behavioral Symptoms / etiology
  • Behavioral Symptoms / rehabilitation*
  • Cognitive Remediation*
  • Dementia / complications
  • Dementia / rehabilitation*
  • Depression / etiology
  • Depression / rehabilitation
  • Female
  • Follow-Up Studies
  • Humans
  • Italy
  • Language
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Outcome Assessment, Health Care*
  • Patient Acuity
  • Quality of Life
  • Residential Facilities
  • Single-Blind Method