Pros and cons of hemi-thyroidectomy for low-risk differentiated thyroid cancer

ANZ J Surg. 2021 Sep;91(9):1704-1710. doi: 10.1111/ans.16553. Epub 2021 Jan 12.

Abstract

The debate regarding the surgical management of low-risk differentiated thyroid cancer (DTC) is ongoing. The recommended extent of surgery in DTC is based on an assessment of the predicted risk of recurrence and recent guidelines reflect an evolving philosophy of de-escalation of surgical management, informed by a growing understanding of the determinants of tumour biology and important prognostic factors. However, our current clinical and pathological risk stratification processes are imperfect and hence there is significant variation in clinical practice. Surgeons face the challenge of finding the balance between avoiding overtreatment, minimizing complications and providing adequate oncological management. This article discusses the nuances of the current management guidelines as well as the important considerations in preoperative decision making.

Keywords: endocrine diseases; general surgery; thyroid neoplasms; thyroidectomy.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma*
  • Humans
  • Neoplasm Recurrence, Local
  • Thyroid Neoplasms* / surgery
  • Thyroidectomy