Short-term outcome of transcutaneous glucocorticoid injection for laryngeal contact granuloma in females

Eur Arch Otorhinolaryngol. 2021 May;278(5):1499-1504. doi: 10.1007/s00405-020-06595-3. Epub 2021 Jan 13.

Abstract

Objective: To evaluate the short-term efficacy of transcutaneous glucocorticoid injection for laryngeal contact granuloma in females.

Methods: A total of 14 female patients with laryngeal contact granuloma treated in our outpatient department from November 2017 to January 2020 were included in the study. Inspiratory-phase laryngoscopy images were collected before treatment and 1 month after each injection, and the lesion size was measured and evaluated with ImageJ software.

Results: Two patients achieved complete remission after one injection, with a percent reduction of 100%. After two injections, 4 patients achieved complete remission, with a percent reduction ranging from 96% to 100%. After 3 injections, 4 patients achieved complete remission (including one patient with bilateral lesions), and the percent reduction ranged from 95% to 100%. Three patients achieved incomplete remission, with a percent reduction of 46%, 55%, and 81%, respectively. In one case, there was no remission, and the granuloma increased in size after treatment.

Conclusion: In women with laryngeal contact granuloma, transcutaneous glucocorticoid injection therapy can quickly resolve the granuloma in a short period.

Keywords: Female; Glucocorticoids; Granuloma; Injections; Therapy; Vocal cords.

MeSH terms

  • Female
  • Glucocorticoids*
  • Granuloma / surgery
  • Granuloma, Laryngeal* / drug therapy
  • Granuloma, Laryngeal* / surgery
  • Humans
  • Laryngoscopy
  • Treatment Outcome
  • Vocal Cords

Substances

  • Glucocorticoids