Does Performing Different Resistance Exercises for the Same Muscle Group Induce Non-homogeneous Hypertrophy?

Int J Sports Med. 2021 Jul;42(9):803-811. doi: 10.1055/a-1308-3674. Epub 2021 Jan 13.


The study aimed to compare the effect of performing the same or different exercises for a muscle group on resistance training (RT) sessions on muscle hypertrophy at different sites along muscle length. Twenty-two detrained men (23.3±4.1 years) were randomly allocated to the following groups: a group that performed the same exercises in all training sessions (N-VAR=11) or one that varied the exercises for the same muscle groups (VAR=11). All were submitted to 3 weekly sessions for nine weeks. Muscle thickness was assessed at the proximal, middle, and distal sites of the lateral and anterior thigh, elbow flexors, and extensors by B-mode ultrasound. The VAR group significantly increased all the sites analyzed (P<0.05). Furthermore, the proximal site of the lateral thigh showed a larger relative increase when compared to the middle site (P<0.05). In contrast, the N-VAR group were not revealed significant improvements only for the middle site of the lateral thigh and the proximal site of the elbow flexors (P>0.05). Our results suggest that to perform different resistance exercises can induce hypertrophy of all sites assessed in detrained young men.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adaptation, Physiological
  • Adult
  • Elbow / physiology
  • Humans
  • Male
  • Muscle Strength*
  • Muscle, Skeletal / growth & development*
  • Resistance Training / methods*
  • Thigh / physiology
  • Ultrasonography
  • Young Adult