Maternal corneal thickness during pregnancy

Am J Ophthalmol. 1988 Mar 15;105(3):258-60. doi: 10.1016/0002-9394(88)90006-2.


We measured central corneal thickness in 89 pregnant women. It was increased 16 micron (P = .01) compared to the control eyes of 18 nongravid and 17 postpartum women. There was no significant difference (P = .79) in corneal thickness between the nongravid and postpartum groups. When comparing subjects by week of gestation, there was no trend over time in corneal thickness (analysis by linear regression). Intraocular pressure was lowered during pregnancy, but it did not correlate with corneal thickness for either the pregnant or nonpregnant group.

MeSH terms

  • Adult
  • Cornea / anatomy & histology*
  • Female
  • Humans
  • Intraocular Pressure
  • Pregnancy / physiology*
  • Pregnancy Trimester, First
  • Pregnancy Trimester, Second
  • Pregnancy Trimester, Third
  • Reference Values