A new class of small inhibitory interneurones in the lamprey spinal cord

Brain Res. 1988 Jan 12;438(1-2):404-7. doi: 10.1016/0006-8993(88)91373-x.


Paired intracellular recordings of interneurones and motoneurones have been performed in the lamprey spinal cord in vitro. One new type of small interneurone (10-15 microns in diameter) which produces monosynaptic inhibitory postsynaptic potentials (IPSPs) in motoneurones is described. The IPSP is strychnine-sensitive and thus presumably glycinergic. This type of interneurone undergoes rhythmical membrane potential oscillations during fictive locomotion and intracellular stimulation can have a profound effect on the burst generation occurring during fictive locomotion.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Electric Stimulation
  • Fishes / anatomy & histology*
  • In Vitro Techniques
  • Interneurons / classification
  • Interneurons / physiology*
  • Lampreys / anatomy & histology*
  • Lampreys / physiology
  • Neural Inhibition*
  • Spinal Cord / cytology
  • Spinal Cord / physiology*