Bowel perforation from malignant atrophic papulosis treated with eculizumab

Ajithraj Sathiyaraj; Priyanga Jayakumar; Matthew R McGlennon; John F Eckford; Sandy Itwaru Anne

doi:10.1080/08998280.2020.1809942

Bowel perforation from malignant atrophic papulosis treated with eculizumab

Proc (Bayl Univ Med Cent). 2020 Sep 14;34(1):111-113. doi: 10.1080/08998280.2020.1809942.

Authors

Ajithraj Sathiyaraj¹, Priyanga Jayakumar², Matthew R McGlennon¹, John F Eckford³, Sandy Itwaru Anne^{3

4}

Affiliations

¹ Department of Internal Medicine, Baylor Scott and White Medical Center - Round Rock, Texas.
² Department of Family Medicine, Baylor Scott and White Medical Center - Round Rock, Texas.
³ Department of General Surgery, Baylor Scott and White Medical Center - Round Rock, Texas.
⁴ Department of Hematology and Oncology, Baylor Scott and White Cancer Center - Round Rock, Texas.

Abstract

We present the case of a 57-year-old man with known cutaneous manifestations of malignant atrophic papulosis, also known as Köhlmeier-Degos disease, who developed an almost-fatal small bowel perforation following a parathyroidectomy. He required two surgical interventions during his initial hospitalization and was started on eculizumab. Despite these therapies, the patient developed recurrent bowel perforations and ultimately died.

Keywords: Bowel perforation; Degos disease; eculizumab; malignant atrophic papulosis.

Publication types

Case Reports