Investigation on the luminescence behavior of terbium acetylsalicylate/bilirubin system via 2D-COS approaches

An-Qi He; Qiang Li; Zhen-Qiang Yu; Jing Tian; Jun Song; Juan Feng; Yi-Zhuang Xu; Isao Noda; Yukihiro Ozaki

doi:10.1016/j.saa.2021.119427

Investigation on the luminescence behavior of terbium acetylsalicylate/bilirubin system via 2D-COS approaches

Spectrochim Acta A Mol Biomol Spectrosc. 2021 Apr 15:251:119427. doi: 10.1016/j.saa.2021.119427. Epub 2021 Jan 5.

Authors

An-Qi He¹, Qiang Li², Zhen-Qiang Yu³, Jing Tian⁴, Jun Song⁵, Juan Feng⁴, Yi-Zhuang Xu⁶, Isao Noda⁷, Yukihiro Ozaki⁸

Affiliations

¹ College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, PR China; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, PR China; Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, PR China.
² College of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, PR China.
³ College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, PR China; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, PR China. Electronic address: zqyu@szu.edu.cn.
⁴ School of Life Science and Technology, University of Electronic Science and Technology, Chengdu, Sichuan 610054, PR China.
⁵ Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, PR China.
⁶ Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, PR China. Electronic address: xyz@pku.edu.cn.
⁷ Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, PR China; Department of Materials Science and Engineering, University of Delaware, Newark, DE 19716, United States.
⁸ Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, PR China; Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, Sanda, Hyogo 669-1337, Japan.

PMID: 33461134
DOI: 10.1016/j.saa.2021.119427

Abstract

Terbium acetylsalicylate has been prepared, and the ethanol solution of the complex exhibits strong luminescence under the excitation of ultraviolet radiation. When a small amount of bilirubin solution is introduced into the solution containing a high concentration of terbium acetylsalicylate, a remarkable diminution of the luminescence of the terbium complex was observed. Investigations on the behavior and life-time of luminescence indicate that the quenching is not caused by forming a stable non-luminescent product via a reaction between terbium acetylsalicylate and bilirubin. A π-π interaction between the chromophore of bilirubin and the aromatic moiety of ligand was revealed via the pattern of cross peaks in the 2D asynchronous spectrum generated using the DAOSD (double asynchronous orthogonal sample design) approach. Such an interaction paves a route for energy transfer in the quenching process. The combination of a high concentration of the terbium complex and a long life-time of luminescence in the lanthanide complex/bilirubin system forms a special scenario: a bilirubin molecule by diffusion may visit and deactivate dozens of excited terbium complexes within the half-life period of the lanthanide complex. This is why a small amount of bilirubin can bring about the significant reduction of luminescence on the solution containing a high concentration of the terbium complex.

Keywords: 2D-COS; Bilirubin; Luminescence; Terbium acetylsalicylate.