Erosion of psoriatic plaques after chronic methotrexate administration

Int J Dermatol. 1988 Jan-Feb;27(1):59-62. doi: 10.1111/j.1365-4362.1988.tb02342.x.

Abstract

A 43-year-old white man developed a shallow erosion of a psoriatic plaque after chronic administration of methotrexate. This unusual cutaneous sign may be the first sign of methotrexate toxicity.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Male
  • Methotrexate / adverse effects*
  • Methotrexate / therapeutic use
  • Psoriasis / drug therapy*
  • Psoriasis / pathology
  • Skin Ulcer / chemically induced*
  • Skin Ulcer / pathology

Substances

  • Methotrexate