Autoimmune Hemolytic Anemia and Pulmonary Embolism: An Association to Consider

Daria Solari; Lorenzo Alberio; Camillo Ribi; Francesco Grandoni; Gregoire Stalder

doi:10.1055/s-0040-1721733

Autoimmune Hemolytic Anemia and Pulmonary Embolism: An Association to Consider

TH Open. 2021 Jan 17;5(1):e8-e13. doi: 10.1055/s-0040-1721733. eCollection 2021 Jan.

Authors

Daria Solari¹, Lorenzo Alberio¹, Camillo Ribi², Francesco Grandoni¹, Gregoire Stalder¹

Affiliations

¹ Division and Central Laboratory of Hematology, Department of Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
² Division of Immunology and Allergy, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

Abstract

Autoimmune hemolytic anemia (AIHA) is increasingly recognized as a strong risk factor for venous thrombosis. However, there are currently no guidelines on thromboembolism prevention and management during AIHA. Here, we describe the case of a patient with AIHA and pulmonary embolism and resume the current knowledge on epidemiology, risk factors, treatment, and pathophysiology of thrombosis during AIHA, as well as new therapeutic perspectives to prevent thrombus formation during AIHA.

Keywords: anticoagulant prophylaxis; autoimmune hemolytic anemia; complication; venous thromboembolism.

The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ).

Publication types

Review