Temperature-dependence of a fast motile response in isolated outer hair cells of the guinea-pig cochlea

Q J Exp Physiol. 1988 Jan;73(1):143-5. doi: 10.1113/expphysiol.1988.sp003114.


Isolated outer hair cells (OHC) of the cochlea exhibit a motility which can be driven at acoustic frequencies (Ashmore, 1987). The temperature-dependence of the movement is reported here for the range 20-37 degrees C. OHC are shown to be motile at 37 degrees C. The temperature-dependence is quite weak, with Q10 = 1.33. The observation is difficult to reconcile with mechanisms involving an intermediate biochemical messenger, including those based on actomyosin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Guinea Pigs
  • Hair Cells, Auditory / physiology*
  • In Vitro Techniques
  • Kinetics
  • Movement
  • Temperature