Sensitive GATA1 mutation screening reliably identifies neonates with Down syndrome at risk for myeloid leukemia

Leukemia. 2021 Aug;35(8):2403-2406. doi: 10.1038/s41375-021-01128-1. Epub 2021 Jan 22.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers, Tumor / genetics*
  • DNA Mutational Analysis
  • Down Syndrome / complications*
  • Early Detection of Cancer / methods*
  • Female
  • Follow-Up Studies
  • GATA1 Transcription Factor / genetics*
  • Humans
  • Infant, Newborn
  • Leukemia, Myeloid / diagnosis*
  • Leukemia, Myeloid / etiology
  • Leukemia, Myeloid / pathology
  • Male
  • Mutation*
  • Prognosis
  • Retrospective Studies

Substances

  • Biomarkers, Tumor
  • GATA1 Transcription Factor
  • GATA1 protein, human