Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML

Leukemia. 2021 Jul;35(7):2119-2124. doi: 10.1038/s41375-021-01125-4. Epub 2021 Jan 22.
No abstract available

Publication types

  • Clinical Trial, Phase II
  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Antimetabolites, Antineoplastic / therapeutic use*
  • Azacitidine / therapeutic use*
  • Cyclopentanes / therapeutic use*
  • Enzyme Inhibitors / therapeutic use*
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myelomonocytic, Chronic / drug therapy*
  • Myelodysplastic Syndromes / drug therapy*
  • Pyrimidines / therapeutic use*

Substances

  • Antimetabolites, Antineoplastic
  • Cyclopentanes
  • Enzyme Inhibitors
  • Pyrimidines
  • Azacitidine
  • pevonedistat

Associated data

  • ClinicalTrials.gov/NCT02610777