Revised recommendations of the Italian Society of Pediatrics about the general management of Kawasaki disease

Ital J Pediatr. 2021 Jan 25;47(1):16. doi: 10.1186/s13052-021-00962-4.


Aim of these revised recommendations for the general management of Kawasaki disease is to encourage its prompter recognition and warrant the most appropriate therapy, based on ascertained scientific data, raising awareness of the complications related to misdiagnosis or delayed treatment. A set of 20 synthetic operative statements is herein provided, including the definition of Kawasaki disease, its protean presentations, clinical course and seminal treatment modalities of all disease phases. The application of these recommendations should improve prognosis of Kawasaki disease and prevent the progression to permanent vascular abnormalities, thereby diminishing morbidity and mortality.

Keywords: Aspirin; Children; Coronary artery abnormalities; Intravenous immunoglobulin; Kawasaki disease.

Publication types

  • Practice Guideline
  • Review

MeSH terms

  • Child
  • Diagnosis, Differential
  • Disease Progression
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Italy
  • Mucocutaneous Lymph Node Syndrome / diagnosis*
  • Mucocutaneous Lymph Node Syndrome / therapy*
  • Prognosis


  • Immunoglobulins, Intravenous