Successful rescue treatment of right posterior inferior cerebellar artery (PICA) vascular stasis with tirofiban following endovascular coil implantation

BMJ Case Rep. 2021 Jan 26;14(1):e238120. doi: 10.1136/bcr-2020-238120.

Abstract

This report describes a patient who developed intraprocedural vascular stasis immediately following elective endovascular coil emboliation. Urgent antiplatelet treatment with the GpIIb/IIIa agent tirofiban was used. It was infused intra-arterially during the procedure, followed by a fixed rate intravenous continuous infusion, and successfully restored normal circulation. There were no reports of further bleeding or haemodynamic compromise during the hospital stay. The patient's condition returned to baseline and he was discharged the following day with no neurological deficits.

Keywords: adult intensive care; drug therapy related to surgery; neuro ITU; neurology; therapeutic indications.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cerebellum / blood supply
  • Cerebral Angiography
  • Endovascular Procedures*
  • Humans
  • Injections, Intra-Arterial
  • Intracranial Aneurysm / surgery*
  • Intraoperative Complications / drug therapy*
  • Male
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors
  • Thromboembolism / drug therapy*
  • Tirofiban / therapeutic use*
  • Vertebral Artery / surgery*

Substances

  • Platelet Aggregation Inhibitors
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Tirofiban