Vaccines to protect Hereford cattle against the cattle tick, Boophilus microplus

Immunology. 1988 Mar;63(3):363-7.


Vaccines made from gut and gut and synganglion tissue dissected from Boophilus microplus gave 87% and 80% protection, respectively, compared with adjuvant-injected controls in cattle against three infestations with 20,000 larval ticks administered over 14 days. A vaccine prepared from synganglion alone did not protect cattle. Ticks collected from vaccinated cattle produced 95% and 91% fewer eggs, respectively, than ticks from control animals. Vaccinated cattle were protected (36%) 7 months after they had been immunized with tick antigens. Antibody responses to the vaccines were detected by enzyme-linked immunosorbent assay (ELISA).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies / analysis
  • Cattle
  • Cattle Diseases / parasitology
  • Cattle Diseases / prevention & control*
  • Parasite Egg Count
  • Tick Infestations / parasitology
  • Tick Infestations / prevention & control
  • Tick Infestations / veterinary*
  • Ticks / immunology*
  • Vaccination*
  • Vaccines*


  • Antibodies
  • Vaccines