Involvement of ocular surface in graft-versus-host disease: An update from immunopathogenesis to treatment

Alice Bruscolini; Magda Gharbiya; Marta Sacchetti; Rocco Plateroti; Massimo Ralli; Antonietta Moramarco; Antonio Greco; Alessandro Lambiase

doi:10.1002/jcp.30304

Involvement of ocular surface in graft-versus-host disease: An update from immunopathogenesis to treatment

J Cell Physiol. 2021 Sep;236(9):6190-6199. doi: 10.1002/jcp.30304. Epub 2021 Jan 28.

Authors

Alice Bruscolini¹, Magda Gharbiya¹, Marta Sacchetti¹, Rocco Plateroti¹, Massimo Ralli¹, Antonietta Moramarco¹, Antonio Greco¹, Alessandro Lambiase¹

Affiliation

¹ Department of Sense Organs, Sapienza University of Rome, Rome, Italy.

PMID: 33507561
DOI: 10.1002/jcp.30304

Abstract

Graft-versus-host disease is a common complication of hematopoietic stem cell transplantation and the ocular surface is a main target of inflammatory reaction.

Keywords: disease management; graft-versus-host disease; immunopathogenesis; keratoconjunctivitis sicca; ocular surface.

Publication types

Review

MeSH terms

Eye / pathology*
Eye Diseases / immunology
Eye Diseases / pathology
Eye Diseases / therapy
Graft vs Host Disease / classification
Graft vs Host Disease / diagnosis
Graft vs Host Disease / immunology*
Graft vs Host Disease / therapy*
Humans