Abstract
We report a case of extranodal mantle cell lymphoma of the testis in a 72-year-old Caucasian man who presented to his physician's office with rapidly enlarging left testicular mass and skin lesions which were subsequently biopsy-proven to be mantle cell lymphoma. We discuss the clinicopathological features and current management in relapsed and refractory settings of this rare presentation of mantle cell lymphoma.
Keywords:
dermatology; malignant and benign haematology; urology.
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
MeSH terms
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Aged
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Antibodies, Monoclonal, Humanized / therapeutic use
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Cisplatin / therapeutic use
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Cyclophosphamide / therapeutic use
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Cytarabine / therapeutic use
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Dexamethasone / therapeutic use
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Doxorubicin / therapeutic use
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Humans
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In Situ Hybridization, Fluorescence
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Lenalidomide / therapeutic use
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Lymphoma, Mantle-Cell / genetics
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Lymphoma, Mantle-Cell / pathology*
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Lymphoma, Mantle-Cell / therapy
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Male
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Oncogene Proteins, Fusion / genetics
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Orchiectomy
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Positron-Emission Tomography
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Prednisone / therapeutic use
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Proto-Oncogene Proteins c-myc / genetics
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Radiotherapy
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Rituximab / therapeutic use
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Skin Neoplasms / genetics
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Skin Neoplasms / pathology*
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Skin Neoplasms / therapy
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Testicular Neoplasms / genetics
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Testicular Neoplasms / pathology*
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Testicular Neoplasms / therapy
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Vincristine / therapeutic use
Substances
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Antibodies, Monoclonal, Humanized
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IGH-CCND1 fusion protein, human
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MYC protein, human
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Oncogene Proteins, Fusion
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Proto-Oncogene Proteins c-myc
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R-CHOP protocol
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Cytarabine
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Rituximab
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Vincristine
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Dexamethasone
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Doxorubicin
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Cyclophosphamide
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Lenalidomide
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obinutuzumab
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Cisplatin
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Prednisone