Impact of Silver Diamine Fluoride Therapy on Oral Health-related Quality of Life of Uncooperative Preschool Children: A Prospective Study

Oral Health Prev Dent. 2021;19(1):93-99. doi: 10.3290/j.ohpd.b927709.


Purpose: Preschool children with early childhood caries (ECC) frequently exhibit extreme dental anxiety and fear, posing a considerable challenge to paediatric dentists for their treatment. The aim of this study was to evaluate the influence of silver diamine fluoride (SDF) treatment on the oral health-related quality of life (OHRQoL) of uncooperative preschool children using an Arabic version of the Early Childhood Oral Health Impact Scale (A-ECOHIS).

Materials and methods: A pre-validated A-ECOHIS was used to assess the sensitivity and responsiveness. Fiftyone children, uncooperative with conventional dental care, underwent SDF treatment; their mothers answered the A-ECOHIS before and 4 weeks after treatment. Based on the global transition rating (GTR), the mothers rated their child's oral health condition following SDF treatment.

Results: SDF effectively arrested caries after 4 weeks in all children. There was a statistically significant reduction in mean scores of the total A-ECOHIS, child impact scale and family impact scores at follow-up (Wilcoxon signedrank test; p ˂ 0.001). There were statistically significant changes in the mean GTR of children's oral health.

Conclusions: A-ECOHIS was sensitive and responsive to SDF treatment. SDF statistically significantly improved the OHRQoL of uncooperative preschool children.

Keywords: children; dental caries; mothers; quality of life; silver diamine fluoride.

MeSH terms

  • Child
  • Child, Preschool
  • Dental Anxiety
  • Dental Caries* / drug therapy
  • Dental Caries* / prevention & control
  • Fear
  • Fluorides, Topical
  • Humans
  • Oral Health
  • Prospective Studies
  • Quality of Life*
  • Quaternary Ammonium Compounds
  • Silver Compounds
  • Surveys and Questionnaires


  • Fluorides, Topical
  • Quaternary Ammonium Compounds
  • Silver Compounds
  • silver diamine fluoride