Diagnosis of Polycystic Ovary Syndrome: Which Criteria to Use and When?

Endocrinol Metab Clin North Am. 2021 Mar;50(1):11-23. doi: 10.1016/j.ecl.2020.10.002.


Current diagnostic criteria for polycystic ovary syndrome (PCOS) are based on expert opinion. This article reviews the rationale for and the limitations of these criteria as well as which criteria to use and when. The insights provided into PCOS pathogenesis by modern genetic analyses and the promise of objective data mining approaches for biologically relevant disease classification are discussed.

Keywords: Diagnostic criteria; Disease classification; Hyperandrogenism; PCOS; Polycystic ovary syndrome.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Female
  • Humans
  • Polycystic Ovary Syndrome* / diagnosis
  • Polycystic Ovary Syndrome* / therapy