Diagnosis of Polycystic Ovary Syndrome: Which Criteria to Use and When?

Sydney Chang; Andrea Dunaif

doi:10.1016/j.ecl.2020.10.002

Diagnosis of Polycystic Ovary Syndrome: Which Criteria to Use and When?

Endocrinol Metab Clin North Am. 2021 Mar;50(1):11-23. doi: 10.1016/j.ecl.2020.10.002.

Authors

Sydney Chang¹, Andrea Dunaif²

Affiliations

¹ Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Zucker School of Medicine at Hofstra/Northwell, 210A E 64th St. 1st Floor, New York, NY 10065, USA.
² Department of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, Atran Building, 1428 Madison Avenue, 4th Floor, Room 4-36, New York, NY 10029, USA. Electronic address: andrea.dunaif@mssm.edu.

Abstract

Current diagnostic criteria for polycystic ovary syndrome (PCOS) are based on expert opinion. This article reviews the rationale for and the limitations of these criteria as well as which criteria to use and when. The insights provided into PCOS pathogenesis by modern genetic analyses and the promise of objective data mining approaches for biologically relevant disease classification are discussed.

Keywords: Diagnostic criteria; Disease classification; Hyperandrogenism; PCOS; Polycystic ovary syndrome.

Diagnosis of Polycystic Ovary Syndrome: Which Criteria to Use and When?

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