Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations

Jacqueline S Dron; Minxian Wang; Aniruddh P Patel; Uri Kartoun; Kenney Ng; Robert A Hegele; Amit V Khera

doi:10.1161/CIRCGEN.120.003182

Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations

Circ Genom Precis Med. 2021 Feb;14(1):e003182. doi: 10.1161/CIRCGEN.120.003182. Epub 2021 Feb 1.

Authors

Jacqueline S Dron^#^{1

2

3

4}, Minxian Wang^#⁴, Aniruddh P Patel^{3

5

4

6}, Uri Kartoun⁷, Kenney Ng⁷, Robert A Hegele^{1

2

8}, Amit V Khera^{3

5

4

6}

Affiliations

¹ Robarts Research Institute (J.S.D., R.A.H.), Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
² Department of Biochemistry (J.S.D., R.A.H.), Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
³ Center for Genomic Medicine (J.S.D., A.P.P., A.V.K.), Massachusetts General Hospital, Boston.
⁴ Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA (J.S.D., M.W., A.P.P., A.V.K.).
⁵ Division of Cardiology (A.P.P., A.V.K.), Massachusetts General Hospital, Boston.
⁶ Department of Medicine, Harvard Medical School, Boston, MA (A.P.P., A.V.K.).
⁷ Center for Computational Health, IBM Research, Cambridge, MA (U.K., K.N.).
⁸ Department of Medicine (R.A.H.), Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

^# Contributed equally.

No abstract available

Keywords: biomarkers; cholesterol; genetic testing; genetics; humans.

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Biological Specimen Banks
Biomarkers / blood
Cardiovascular Diseases / diagnosis*
Cardiovascular Diseases / genetics
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Humans
Lipoprotein(a) / blood
Lipoprotein(a) / genetics*
United Kingdom
White People / genetics

Substances

Biomarkers
Lipoprotein(a)

Publication types

MeSH terms

Substances

Grants and funding