Surgical management of paratesticular rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, European paediatric Soft tissue sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe

Pediatr Blood Cancer. 2021 Apr;68(4):e28938. doi: 10.1002/pbc.28938. Epub 2021 Feb 1.


The treatment of paratesticular rhabdomyosarcoma (PT-RMS) has varied over time and by cooperative group. The International Soft Tissue Sarcoma Database Consortium (INSTRuCT) is a collaboration of the Children's Oncology Group (COG) Soft Tissue Sarcoma Committee, European pediatric Soft tissue sarcoma Study Group (EpSSG), and the Cooperative Weichteilsarkom Studiengruppe (CWS). The INSTRuCT surgical committee has been given charge of the development of internationally applicable consensus guidelines for the surgical treatment of rhabdomyosarcoma. This clinical consensus opinion document addresses accepted principles and areas of controversy, such as scrotal violation and retroperitoneal nodal evaluation, providing an evidence-based guideline for the surgical treatment for PT-RMS.

Keywords: international; paratesticular; pediatric; rhabdomyosarcoma.

Publication types

  • Practice Guideline
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Disease Management
  • Europe
  • Humans
  • Lymph Nodes / pathology
  • Lymph Nodes / surgery
  • Male
  • Prognosis
  • Rhabdomyosarcoma / diagnosis
  • Rhabdomyosarcoma / surgery*
  • Rhabdomyosarcoma, Embryonal / diagnosis
  • Rhabdomyosarcoma, Embryonal / surgery
  • Scrotum / pathology
  • Scrotum / surgery
  • Testicular Neoplasms / diagnosis
  • Testicular Neoplasms / surgery*