Subject and partner satisfaction with lip and perioral enhancement using flexible hyaluronic acid fillers

J Cosmet Dermatol. 2021 May;20(5):1499-1504. doi: 10.1111/jocd.13956. Epub 2021 Feb 1.


Background: The injection of hyaluronic acid (HA) dermal fillers is a popular minimally invasive approach to improve lip volume and contour, and with improved techniques has gained popularity because full lips are often associated with beauty and youth. Patient satisfaction is a key driver for successful aesthetic procedures, influencing individual treatment plans and future recommendations.

Objective: To evaluate subject and partner satisfaction with the hyaluronic acid (HA) dermal filler HARK for lip enhancement at 8 weeks after the last treatment.

Methods & materials: Subjects in this open-label study all received HARK in the lips, and an additional group also received HARR and/or HARD in nasolabial folds (NLFs) and marionette lines (MLs). Satisfaction was assessed at Weeks 4 and 8 after the last treatment using questionnaires (FACE-Q™ [subjects] and KISSABILITY [subjects and partners]).

Results: Nineteen subjects received HARK only; 40 also received HARR and/or HARD . Subjects reported a high level of satisfaction with their lips following treatment. Increases from baseline in the mean total satisfaction score were statistically significant at Weeks 4 and 8 (P ≤ .001). Most subjects (≥89%) reported satisfaction on all FACE-Q questions at Week 8. Both subjects and partners were satisfied with the kissability, appearance, and natural look and feel of the post-treatment results.

Conclusion: This study demonstrated that HARK resulted in lip enhancement with high levels of subject and partner satisfaction, when used alone or in combination with HARR / HARD in NLFs and MLs.

Keywords: dermal fillers; flexible filler; hyaluronic acid; lip filler; partner satisfaction; patient satisfaction.

MeSH terms

  • Adolescent
  • Cosmetic Techniques*
  • Dermal Fillers*
  • Humans
  • Hyaluronic Acid
  • Lip
  • Nasolabial Fold
  • Patient Satisfaction
  • Personal Satisfaction
  • Rejuvenation
  • Skin Aging*
  • Treatment Outcome


  • Dermal Fillers
  • Hyaluronic Acid

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