Development of an ethanolic two-phase system (ETPS) based on polypropylene glycol 2000 + ethylene glycol + ethanol for separation of hydrophobic compounds

Filipe Smith Buarque; Cleide Mara Faria Soares; Ranyere Lucena de Souza; Matheus Mendonça Pereira; Álvaro Silva Lima

doi:10.1039/d0cc01542c

Development of an ethanolic two-phase system (ETPS) based on polypropylene glycol 2000 + ethylene glycol + ethanol for separation of hydrophobic compounds

Chem Commun (Camb). 2021 Mar 1;57(17):2156-2159. doi: 10.1039/d0cc01542c.

Authors

Filipe Smith Buarque¹, Cleide Mara Faria Soares², Ranyere Lucena de Souza², Matheus Mendonça Pereira³, Álvaro Silva Lima²

Affiliations

¹ Tiradentes University, Av. Murilo Dantas, 300, CEP: 49032-490, Aracaju, SE, Brazil. alvaro_lima@itp.org.br.
² Tiradentes University, Av. Murilo Dantas, 300, CEP: 49032-490, Aracaju, SE, Brazil. alvaro_lima@itp.org.br and Institute of Technology and Research, Av. Murilo Dantas, 300, Prédio do ITP, CEP: 49032-490, Aracaju, SE, Brazil.
³ CICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, Campus Universitario de Santiago, 3810-193 Aveiro, Portugal.

PMID: 33523051
DOI: 10.1039/d0cc01542c

Abstract

This work reports, for the first time, an Ethanolic Two-Phase System (ETPS) based on polypropylene glycol 2000 (PPG 2000), mono-, di-, tri-ethylene glycol, and ethanol. An ionic liquid (IL) (1-butyl-3-methylpyridinium chloride) was used as an adjuvant. This ETPS shows promising results for the extraction of highly hydrophobic compounds. Bixin (model of hydrophobic compounds) migrates completely to the PPG 2000-rich phase, while ascorbic acid (hydrophilic compound) migrated to the opposite phase.