Pathogen-Reservoir Interactions: What We Do Not Know Likely Will Hurt Us

Viruses. 2021 Jan 28;13(2):195. doi: 10.3390/v13020195.

Abstract

The establishment of selective colonies of potential vertebrate hosts for viruses would provide experimental models for the understanding of pathogen-host interactions. This paper briefly surveys the reasons to conduct such studies and how the results might provide information that could be applied to disease prevention activities.

Keywords: SARS-CoV-2; anthroponosis; bats; coronavirus; experimental infections; pathogenesis; reservoir; reverse transmission; zoonosis.

MeSH terms

  • Animals
  • COVID-19 / prevention & control
  • COVID-19 / transmission
  • COVID-19 / virology
  • Chiroptera / virology
  • Coronavirus / classification
  • Coronavirus / genetics
  • Coronavirus / pathogenicity
  • Disease Reservoirs / virology*
  • Host Specificity
  • Host-Pathogen Interactions*
  • Humans
  • SARS-CoV-2 / classification
  • SARS-CoV-2 / genetics
  • SARS-CoV-2 / pathogenicity
  • Zoonoses / prevention & control
  • Zoonoses / virology