Challenges and Opportunities in Multimodal Monitoring and Data Analytics in Traumatic Brain Injury

Curr Neurol Neurosci Rep. 2021 Feb 2;21(3):6. doi: 10.1007/s11910-021-01098-y.


Purpose of review: Increasingly sophisticated systems for monitoring the brain have led to an increase in the use of multimodality monitoring (MMM) to detect secondary brain injuries before irreversible damage occurs after brain trauma. This review examines the challenges and opportunities associated with MMM in this population.

Recent findings: Locally and internationally, the use of MMM varies. Practical challenges include difficulties with data acquisition, curation, and harmonization with other data sources limiting collaboration. However, efforts toward integration of MMM data, advancements in data science, and the availability of cloud-based infrastructures are now affording the opportunity for MMM to advance the care of patients with brain trauma. MMM provides data to guide the precision management of patients with traumatic brain injury in real time. While challenges exist, there are exciting opportunities for MMM to live up to this promise and to drive new insights into the physiology of the brain and beyond.

Keywords: Big data; Brain trauma; EEG; ICP; ICU; Multimodality monitoring.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Brain
  • Brain Injuries* / diagnosis
  • Brain Injuries, Traumatic* / diagnostic imaging
  • Brain Injuries, Traumatic* / therapy
  • Data Science
  • Humans
  • Intracranial Pressure
  • Monitoring, Physiologic