Craniopharyngiomas are benign tumors of neuroepithelial origin, believed to arise from remnants of Rathke's pouch. Their proximity to vital structures of the visual pathway and hypothalamus leads to both neurological and endocrinological complications. Endocrinal complications are seen in 40%-87% of the affected and can develop at presentation or post-surgery and radiotherapy. Central diabetes insipidus (CDI) is a common endocrinopathy associated with craniopharyngioma, but rarely a presenting symptom before or after surgery. CDI most commonly presents with polyuria and polydipsia. Here, we report a postoperative child with craniopharyngioma where recurrent urinary tract infection and hydronephrosis were initial clues to diagnose CDI.
Keywords: Central diabetes insipidus; endocrine disorder; pituitary hormone deficiency; polyuria.
Copyright: © 2020 Journal of Pediatric Neurosciences.