Primary Dermal Melanoma: A Rare Clinicopathological Variant Mimicking Metastatic Melanoma

Dermatopathology (Basel). 2021 Feb 1;8(1):29-32. doi: 10.3390/dermatopathology8010005.


Primary dermal melanoma (PDM) is a rare distinct variant of cutaneous melanoma, predominantly occurring on the extremities of young or middle-aged adults. In comparison to conventional melanoma, PDM is characterized by unexpectedly prolonged survival and long-term survival. Thus, correct identification of this variant is crucial to avoid potential misdiagnosis and establish correct treatment and follow-up. In addition, no consensus and specific guidelines exist on the management of this peculiar subtype of cutaneous melanoma.

Keywords: cutaneous melanoma; cutaneous metastatic melanoma; dermal melanoma; histopathologic diagnosis; primary dermal melanoma; prognosis.

Publication types

  • Case Reports