Clinical Symptoms Among Ambulatory Patients Tested for SARS-CoV-2

Open Forum Infect Dis. 2020 Nov 26;8(1):ofaa576. doi: 10.1093/ofid/ofaa576. eCollection 2021 Jan.


We compared symptoms and characteristics of 4961 ambulatory patients with and without laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection. Findings indicate that clinical symptoms alone would be insufficient to distinguish between coronavirus disease 2019 and other respiratory infections (eg, influenza) and/or to evaluate the effects of preventive interventions (eg, vaccinations).

Keywords: COVID-19; case definitions; influenza; observational research studies; vaccine effectiveness.