Improving Methods to Classify Perinatal versus Nonperinatal HIV Acquisition in Young Adolescents 10-14 Years of Age

Pediatr Infect Dis J. 2021 May 1;40(5):453-456. doi: 10.1097/INF.0000000000003059.


Mode of HIV acquisition for adolescents with HIV is often not recorded within routine healthcare databases. Hence, age at enrollment in HIV care is often used as a proxy for perinatal versus nonperinatal infection. Using routine cohort data from adolescents presenting for HIV care 10-14 years of age, we developed logistic regression models to predict likely mode of infection.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Age Factors
  • Area Under Curve
  • Child
  • Disease Transmission, Infectious / classification*
  • Female
  • HIV Infections / epidemiology*
  • HIV Infections / etiology*
  • HIV Infections / transmission*
  • Humans
  • Infectious Disease Transmission, Vertical
  • Male
  • Predictive Value of Tests
  • ROC Curve
  • Routinely Collected Health Data