Progress in Prevention, Diagnosis, and Treatment of Periprosthetic Joint Infection

Kai Wang; Wei Li; Huayu Liu; Yang Yang; Lingyun Lv

doi:10.1155/2021/3023047

Progress in Prevention, Diagnosis, and Treatment of Periprosthetic Joint Infection

Evid Based Complement Alternat Med. 2021 Jan 20:2021:3023047. doi: 10.1155/2021/3023047. eCollection 2021.

Authors

Kai Wang¹, Wei Li², Huayu Liu², Yang Yang¹, Lingyun Lv³

Affiliations

¹ International Medicine Center, Tianjin Hospital, 406 Jiefang South Road, Hexi District, Tianjin 300211, China.
² College of Light Industry Science and Engineering, Tianjin University of Science and Technology, Tianjin 30045, China.
³ Department of Otorhinolaryngology-Head and Neck Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huaian 223300, China.

Abstract

Periprosthetic joint infection (PJI) after joint replacement surgery is a severe complication associated with high morbidity and increased treatment costs. More than 25% of joint implant failures are attributed to PJI. PJI diagnosis and treatment methods have substantially improved in recent years. However, the prevalence of PJI remains high, primarily due to the increased prevalences of obesity, diabetes, and other underlying conditions. Moreover, increasing elderly prefers to total joint replacement surgery. However, due to frailty and comorbidities, most are at increased risk of infectious arthritis and artificial joint infection (PJI). Therefore, PJI management for the elderly requires multilevel and multiangle intervention. In this review, we summarize the risk factors and diagnostic methods currently available for PJI and discuss the current PJI prevention and treatment interventions, especially the management in older adults.

Publication types

Review