Electromembrane extraction of peptides and amino acids - status and perspectives

Bioanalysis. 2021 Feb;13(4):277-289. doi: 10.4155/bio-2020-0285. Epub 2021 Feb 5.


This article reviews the scientific literature on electromembrane extraction (EME) of peptides and amino acids. In EME, target analytes are extracted from aqueous sample, through a supported liquid membrane (organic) and into a microliter volume of aqueous buffer (acceptor). Experimental conditions and performance for EME of peptides and amino acids are reviewed and discussed in detail, providing readers with an overview and basic understanding of the subject. In addition, this review discuss the potential for future applications, and scientific questions that need to be addressed for EME of peptides and amino acids to be generally accepted. EME is under commercialization, and therefore we expect it will be an active area of research in the near future.

Keywords: amino acids; biological samples; electromembrane extraction; peptides; selective extraction.