Synchronous Multifocal Canalicular Adenomas

Ahmed S Sultan; Frank S-C Chang; Tom Cooper; Maryam Jessri

doi:10.1007/s12105-021-01293-w

Synchronous Multifocal Canalicular Adenomas

Head Neck Pathol. 2021 Sep;15(3):945-949. doi: 10.1007/s12105-021-01293-w. Epub 2021 Feb 5.

Authors

Ahmed S Sultan¹, Frank S-C Chang^{2

3

4}, Tom Cooper^{2

3

4}, Maryam Jessri⁵

Affiliations

¹ School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA.
² Department of Oral and Maxillofacial Surgery, Fiona Stanley Hospital, Murdoch, WA, Australia.
³ Department of Oral and Maxillofacial Surgery, Royal Perth Hospital, Perth, WA, Australia.
⁴ Department of Oral and Maxillofacial Surgery, Oral Health Centre of Western Australia, Perth, WA, Australia.
⁵ Department of Oral Medicine, Oral Health Centre of Western Australia, Perth, WA, Australia. maryam_jessri@alumni.harvard.edu.

Abstract

Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.

Keywords: Benign salivary gland tumour; Minor salivary glands; Multifocal canalicular adenoma.

Publication types

Case Reports

MeSH terms

Adenoma / pathology*
Aged, 80 and over
Female
Humans
Mouth Mucosa / pathology*
Salivary Gland Neoplasms / pathology*