Recent Advances in p53

Biomolecules. 2021 Feb 3;11(2):211. doi: 10.3390/biom11020211.

Abstract

Tumor suppressor protein p53 (TP53) is a key transcription factor that, in response to various stress signals, regulates numerous genes involved in a broad range of cellular functions including DNA repair, apoptosis, cell cycle arrest, senescence, metabolism, etc [...].

Publication types

  • Editorial

MeSH terms

  • Animals
  • Apoptosis / genetics
  • Cell Cycle
  • Cell Cycle Checkpoints
  • DNA Repair
  • Disease Progression
  • Genes, p53*
  • Humans
  • Mutation*
  • Neoplasms / genetics*
  • Neoplasms / metabolism
  • Prognosis
  • RNA, Untranslated / metabolism
  • Saccharomyces cerevisiae / metabolism
  • Tumor Suppressor Protein p53 / metabolism*

Substances

  • RNA, Untranslated
  • TP53 protein, human
  • Tumor Suppressor Protein p53