The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder

Neurosci Biobehav Rev. 2021 Sep:128:789-818. doi: 10.1016/j.neubiorev.2021.01.022. Epub 2021 Feb 4.

Abstract

Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base.

Methods: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder.

Results: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents.

Conclusions: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

Keywords: ADHD; Brain; Course; Diagnosis; Genetics; Outcome; Treatment.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Attention Deficit Disorder with Hyperactivity* / therapy
  • Humans
  • Network Meta-Analysis
  • Publication Bias