Shaping the Future of Probiotics and Prebiotics

Trends Microbiol. 2021 Aug;29(8):667-685. doi: 10.1016/j.tim.2021.01.003. Epub 2021 Feb 4.


Recent and ongoing developments in microbiome science are enabling new frontiers of research for probiotics and prebiotics. Novel types, mechanisms, and applications currently under study have the potential to change scientific understanding as well as nutritional and healthcare applications of these interventions. The expansion of related fields of microbiome-targeted interventions, and an evolving landscape for implementation across regulatory, policy, prescriber, and consumer spheres, portends an era of significant change. In this review we examine recent, emerging, and anticipated trends in probiotic and prebiotic science, and create a vision for broad areas of developing influence in the field.

Keywords: future trends; microbiome; personalised; prebiotics; precision; probiotics.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteria / genetics*
  • Bacteria / metabolism
  • Gastrointestinal Microbiome / genetics
  • Gastrointestinal Microbiome / physiology*
  • Humans
  • Prebiotics*
  • Precision Medicine / methods
  • Precision Medicine / trends
  • Probiotics*


  • Prebiotics