Searching for the Optimal Exercise Training Regimen in Heart Failure With Preserved Ejection Fraction

doi:10.1001/jama.2020.26347

Editorial

. 2021 Feb 9;325(6):537-539.

doi: 10.1001/jama.2020.26347.

Searching for the Optimal Exercise Training Regimen in Heart Failure With Preserved Ejection Fraction

Ambarish Pandey¹, Dalane W Kitzman²

Affiliations

¹ Division of Cardiology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
² Cardiovascular Medicine and Geriatrics Sections, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

PMID: 33560307
PMCID: PMC8261711
DOI: 10.1001/jama.2020.26347

Editorial

Searching for the Optimal Exercise Training Regimen in Heart Failure With Preserved Ejection Fraction

Ambarish Pandey et al. JAMA. 2021.

. 2021 Feb 9;325(6):537-539.

doi: 10.1001/jama.2020.26347.

Authors

Ambarish Pandey¹, Dalane W Kitzman²

Affiliations

¹ Division of Cardiology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
² Cardiovascular Medicine and Geriatrics Sections, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

PMID: 33560307
PMCID: PMC8261711
DOI: 10.1001/jama.2020.26347

No abstract available

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Comment on

Effect of High-Intensity Interval Training, Moderate Continuous Training, or Guideline-Based Physical Activity Advice on Peak Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.
Mueller S, Winzer EB, Duvinage A, Gevaert AB, Edelmann F, Haller B, Pieske-Kraigher E, Beckers P, Bobenko A, Hommel J, Van de Heyning CM, Esefeld K, von Korn P, Christle JW, Haykowsky MJ, Linke A, Wisløff U, Adams V, Pieske B, van Craenenbroeck EM, Halle M; OptimEx-Clin Study Group. Mueller S, et al. JAMA. 2021 Feb 9;325(6):542-551. doi: 10.1001/jama.2020.26812. JAMA. 2021. PMID: 33560320 Free PMC article. Clinical Trial.

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Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction: The INABLE-Training Trial.
Borlaug BA, Koepp KE, Reddy YNV, Obokata M, Sorimachi H, Freund M, Haberman D, Sweere K, Weber KL, Overholt EA, Safe BA, Omote K, Omar M, Popovic D, Acker NG, Gladwin MT, Olson TP, Carter RE. Borlaug BA, et al. Mayo Clin Proc. 2024 Feb;99(2):206-217. doi: 10.1016/j.mayocp.2023.08.031. Epub 2023 Dec 21. Mayo Clin Proc. 2024. PMID: 38127015 Clinical Trial.
A Randomized, Controlled Trial of Resistance Training Added to Caloric Restriction Plus Aerobic Exercise Training in Obese Heart Failure With Preserved Ejection Fraction.
Brubaker PH, Nicklas BJ, Houston DK, Hundley WG, Chen H, Molina AJA, Lyles WM, Nelson B, Upadhya B, Newland R, Kitzman DW. Brubaker PH, et al. Circ Heart Fail. 2023 Feb;16(2):e010161. doi: 10.1161/CIRCHEARTFAILURE.122.010161. Epub 2022 Oct 31. Circ Heart Fail. 2023. PMID: 36314122 Free PMC article. Clinical Trial.
Physical activity, cardiorespiratory fitness, and cardiovascular health: A clinical practice statement of the American Society for Preventive Cardiology Part II: Physical activity, cardiorespiratory fitness, minimum and goal intensities for exercise training, prescriptive methods, and special patient populations.
Franklin BA, Eijsvogels TMH, Pandey A, Quindry J, Toth PP. Franklin BA, et al. Am J Prev Cardiol. 2022 Oct 13;12:100425. doi: 10.1016/j.ajpc.2022.100425. eCollection 2022 Dec. Am J Prev Cardiol. 2022. PMID: 36281325 Free PMC article. Review.
Isolated knee extensor exercise training improves skeletal muscle vasodilation, blood flow, and functional capacity in patients with HFpEF.
Hearon CM Jr, Samels M, Dias KA, MacNamara JP, Levine BD, Sarma S. Hearon CM Jr, et al. Physiol Rep. 2022 Aug;10(15):e15419. doi: 10.14814/phy2.15419. Physiol Rep. 2022. PMID: 35924338 Free PMC article.
Heart failure with preserved ejection fraction update: A review of clinical trials and new therapeutic considerations.
Maryniak A, Maisuradze N, Ahmed R, Biskupski P, Jayaraj J, Budzikowski AS. Maryniak A, et al. Cardiol J. 2022;29(4):670-679. doi: 10.5603/CJ.a2022.0051. Epub 2022 Jun 28. Cardiol J. 2022. PMID: 35762077 Free PMC article. Review.

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References

1. Borlaug BA. Evaluation and management of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2020;17(9):559–573. doi:10.1038/s41569-020-0363-2 - DOI - PubMed
1. Shah SJ, Kitzman DW, Borlaug BA, et al. Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap. Circulation. 2016;134(1):73–90. doi:10.1161/CIRCULATIONAHA.116.021884 - DOI - PMC - PubMed
1. Pandey A, Patel KV, Bahnson JL, et al.; Look AHEAD Research Group. Association of intensive lifestyle intervention, fitness, and body mass index with risk of heart failure in overweight or obese adults with type 2 diabetes mellitus: an analysis from the Look AHEAD Trial. Circulation. 2020;141 (16):1295–1306. doi:10.1161/CIRCULATIONAHA.119.044865 - DOI - PubMed
1. Kitzman DW, Brubaker P, Morgan T, et al. Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial. JAMA. 2016;315(1):36–46. doi:10.1001/jama.2015.17346 - DOI - PMC - PubMed
1. Edelmann F, Gelbrich G, Düngen HD, et al. Exercise training improves exercise capacity and diastolic function in patients with heart failure with preserved ejection fraction: results of the Ex-DHF (Exercise Training in Diastolic Heart Failure) pilot study. J Am Coll Cardiol. 2011;58(17):1780–1791. doi: 10.1016/j.jacc.2011.06.054 - DOI - PubMed

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[1] Borlaug BA. Evaluation and management of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2020;17(9):559–573. doi:10.1038/s41569-020-0363-2 - DOI - PubMed

[2] Borlaug BA. Evaluation and management of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2020;17(9):559–573. doi:10.1038/s41569-020-0363-2 - DOI - PubMed

[3] Shah SJ, Kitzman DW, Borlaug BA, et al. Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap. Circulation. 2016;134(1):73–90. doi:10.1161/CIRCULATIONAHA.116.021884 - DOI - PMC - PubMed

[4] Shah SJ, Kitzman DW, Borlaug BA, et al. Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap. Circulation. 2016;134(1):73–90. doi:10.1161/CIRCULATIONAHA.116.021884 - DOI - PMC - PubMed

[5] Pandey A, Patel KV, Bahnson JL, et al.; Look AHEAD Research Group. Association of intensive lifestyle intervention, fitness, and body mass index with risk of heart failure in overweight or obese adults with type 2 diabetes mellitus: an analysis from the Look AHEAD Trial. Circulation. 2020;141 (16):1295–1306. doi:10.1161/CIRCULATIONAHA.119.044865 - DOI - PubMed

[6] Pandey A, Patel KV, Bahnson JL, et al.; Look AHEAD Research Group. Association of intensive lifestyle intervention, fitness, and body mass index with risk of heart failure in overweight or obese adults with type 2 diabetes mellitus: an analysis from the Look AHEAD Trial. Circulation. 2020;141 (16):1295–1306. doi:10.1161/CIRCULATIONAHA.119.044865 - DOI - PubMed

[7] Kitzman DW, Brubaker P, Morgan T, et al. Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial. JAMA. 2016;315(1):36–46. doi:10.1001/jama.2015.17346 - DOI - PMC - PubMed

[8] Kitzman DW, Brubaker P, Morgan T, et al. Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial. JAMA. 2016;315(1):36–46. doi:10.1001/jama.2015.17346 - DOI - PMC - PubMed

[9] Edelmann F, Gelbrich G, Düngen HD, et al. Exercise training improves exercise capacity and diastolic function in patients with heart failure with preserved ejection fraction: results of the Ex-DHF (Exercise Training in Diastolic Heart Failure) pilot study. J Am Coll Cardiol. 2011;58(17):1780–1791. doi: 10.1016/j.jacc.2011.06.054 - DOI - PubMed

[10] Edelmann F, Gelbrich G, Düngen HD, et al. Exercise training improves exercise capacity and diastolic function in patients with heart failure with preserved ejection fraction: results of the Ex-DHF (Exercise Training in Diastolic Heart Failure) pilot study. J Am Coll Cardiol. 2011;58(17):1780–1791. doi: 10.1016/j.jacc.2011.06.054 - DOI - PubMed

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Searching for the Optimal Exercise Training Regimen in Heart Failure With Preserved Ejection Fraction

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Searching for the Optimal Exercise Training Regimen in Heart Failure With Preserved Ejection Fraction

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