Cutaneous manifestations of COVID-19

Dermatol Online J. 2021 Jan 15;27(1):13030/qt2m54r7nv.


The severe acute respiratory syndrome coronavirus two (SARS-CoV-2), which causes the 2019 coronavirus disease (COVID-19), has infected patients worldwide. Physicians have increasingly identified cutaneous findings as a significant clinical manifestation of COVID-19. In this review, we describe the clinical presentation, onset, duration, associated symptoms, treatment, and outcome of cutaneous manifestations thus far reported to be related to COVID-19. We have included data from 63 studies and subdivided reported cutaneous manifestations into the categories of viral exanthem, urticarial, vesicular, chilblains/chilblains-like, non-chilblains vasculopathy-related, pityriasis rosea-like, erythema multiforme-like, Kawasaki/Kawasaki-like disease, and others. Physicians should be aware of the known common cutaneous manifestations of COVID-19 and future research is required to better understand the pathophysiology and prognosis of each COVID-19-related skin manifestation.

Publication types

  • Review

MeSH terms

  • COVID-19 / physiopathology*
  • Chilblains / physiopathology
  • Erythema Multiforme / physiopathology
  • Exanthema / physiopathology
  • Humans
  • Mucocutaneous Lymph Node Syndrome / physiopathology
  • Pityriasis Rosea / physiopathology
  • SARS-CoV-2
  • Skin Diseases / physiopathology*
  • Skin Diseases, Vascular / physiopathology
  • Skin Diseases, Vesiculobullous / physiopathology
  • Systemic Inflammatory Response Syndrome / physiopathology
  • Urticaria / physiopathology

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related