Regional mapping of the human placental alkaline phosphatase gene (ALPP) to 2q37 by in situ hybridization

Cytogenet Cell Genet. 1988;47(1-2):98-9. doi: 10.1159/000132518.

Abstract

In order to determine the subchromosomal location of the gene for human placental alkaline phosphatase (ALPP; EC 3.1.3.1.), a cDNA probe encompassing most of the ALPP translated sequences was hybridized in situ to metaphase chromosomes. Our results confirm previous assignment of the gene to chromosome 2 and allow its regional mapping to band q37.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaline Phosphatase / genetics*
  • Chromosome Mapping
  • Chromosomes, Human, Pair 2* / ultrastructure
  • DNA / genetics
  • GPI-Linked Proteins
  • Genes
  • Humans
  • Isoenzymes / genetics*

Substances

  • GPI-Linked Proteins
  • Isoenzymes
  • DNA
  • Alkaline Phosphatase
  • alkaline phosphatase, placental