[Successful treatment with paclitaxel of a visceral relapse of post-transplant Kaposi's sarcoma]

Nephrol Ther. 2021 Apr;17(2):132-136. doi: 10.1016/j.nephro.2020.10.010. Epub 2021 Feb 6.
[Article in French]

Abstract

We report the observation of a patient who presented with post-transplant Kaposi's sarcoma after a delay of eight months with a dual cutaneous and palatal localisation. The reduction in immunosuppressive treatment and the introduction of Rapamune® allowed good clinical progress initially with regression of the skin lesions. He subsequently presented later a skin relapse with visceral localisation. Chemotherapy was conducted based on weekly paclitaxel infusions allowing partial remission and maintenance of renal graft function with good clinical tolerance.

Keywords: Kaposi's sarcoma; Kidney transplantation; Paclitaxel; Sarcome de Kaposi; Transplantation rénale.

MeSH terms

  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Kidney Transplantation*
  • Male
  • Neoplasm Recurrence, Local / drug therapy
  • Paclitaxel
  • Sarcoma, Kaposi* / drug therapy
  • Sarcoma, Kaposi* / etiology

Substances

  • Immunosuppressive Agents
  • Paclitaxel