Emergence of a Novel SARS-CoV-2 Variant in Southern California

JAMA. 2021 Apr 6;325(13):1324-1326. doi: 10.1001/jama.2021.1612.


This research describes findings of sequencing and phylogenetic analyses of SARS-CoV-2 isolates from symptomatic patients cared for at Cedar-Sinai Medical Center in November-December 2020 during a regional surge in cases and hospitalizations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 / virology*
  • California
  • Humans
  • Mutation
  • SARS-CoV-2 / genetics*
  • SARS-CoV-2 / isolation & purification
  • Sequence Analysis, RNA
  • Spike Glycoprotein, Coronavirus


  • Spike Glycoprotein, Coronavirus