CSF Rhinorrhea: A Rare Clinical Presentation of Choroid Plexus Papilloma

Layth Mula-Hussain; Julia Malone; Marlise P Dos Santos; John Sinclair; Shawn Malone

doi:10.3390/curroncol28010073

CSF Rhinorrhea: A Rare Clinical Presentation of Choroid Plexus Papilloma

Curr Oncol. 2021 Jan 31;28(1):750-756. doi: 10.3390/curroncol28010073.

Authors

Layth Mula-Hussain¹, Julia Malone¹, Marlise P Dos Santos², John Sinclair³, Shawn Malone¹

Affiliations

¹ Radiation Oncology Division, The Ottawa Hospital-University of Ottawa, Ottawa, ON K1H 8L6, Canada.
² Department of Medical Imaging, The Ottawa Hospital-University of Ottawa, and Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
³ Neuro-Surgery Division, The Ottawa Hospital-University of Ottawa, Ottawa, ON K1Y 4E9, Canada.

Abstract

Choroid plexus papilloma (CPP) is a rare brain tumour occurring mostly in infants and children. Most CPPs are intraventricular and present with symptoms and signs of increased intracranial pressure (ICP). This case report describes a middle-aged female who presented with spontaneous cerebrospinal fluid (CSF) rhinorrhea from a tumour located in the cerebellopontine angle (CPA). She underwent craniotomy with subtotal tumour resection and remained progression and rhinorrhea-free for several years. Upon clinical progression, the patient was treated with Cyberknife stereotactic radiosurgery. The patient clinically improved and demonstrated a favourable radiologic response to radiosurgery.

Keywords: CSF rhinorrhea; cerebellopontine angle; choroid plexus tumour; stereotactic radiosurgery.

Publication types

Case Reports

MeSH terms

Brain Neoplasms*
Cerebellopontine Angle
Child
Female
Humans
Middle Aged
Papilloma, Choroid Plexus* / complications
Papilloma, Choroid Plexus* / diagnosis
Papilloma, Choroid Plexus* / surgery
Radiosurgery*
Rhinorrhea