Australian Rotavirus Surveillance Program: Annual Report, 2018

Commun Dis Intell (2018). 2021 Jan 29:45. doi: 10.33321/cdi.2021.45.6.

Abstract

This report, from the Australian Rotavirus Surveillance Program and collaborating laboratories Australia-wide, describes the rotavirus genotypes identified in children and adults with acute gastroenteritis during the period 1 January to 31 December 2018. During this period, 690 faecal specimens were referred for rotavirus G- and P- genotype analysis, including 607 samples that were confirmed as rotavirus positive. Of these, 457/607 were wild-type rotavirus strains and 150/607 were identified as rotavirus vaccine-like. Genotype analysis of the 457 wild-type rotavirus samples from both children and adults demonstrated that G3P[8] was the dominant genotype nationally, identified in 52% of samples, followed by G2P[4] (17%). The Australian National Immunisation Program, which previously included both RotaTeq and Rotarix vaccines, changed to Rotarix exclusively on 1 July 2017. Continuous surveillance is needed to identify if the change in vaccination schedule could affect rotavirus genotype distribution and diversity in Australia.

Keywords: Australia; G3; G3P[8]; G9; P[25]; P[8]; RotaTeq; Rotarix; gastroenteritis; genotype; mis-priming; mis-typing; primer slippage; rotavirus; surveillance; vaccine.

MeSH terms

  • Australia / epidemiology
  • Child, Preschool
  • Epidemiological Monitoring
  • Feces / virology
  • Female
  • Gastroenteritis / epidemiology
  • Gastroenteritis / virology
  • Genotype
  • Humans
  • Immunization Programs
  • Infant
  • Infant, Newborn
  • Male
  • Population Surveillance
  • Rotavirus / genetics
  • Rotavirus / immunology
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / prevention & control*
  • Rotavirus Infections / virology
  • Rotavirus Vaccines / administration & dosage
  • Rotavirus Vaccines / immunology*
  • Vaccines, Attenuated

Substances

  • RIX4414 vaccine
  • RotaTeq
  • Rotavirus Vaccines
  • Vaccines, Attenuated